![]() It has been postulated that sodium thiosulfate: (i) forms with calcium a more soluble complex than calcium phosphate and calcium oxalate, (ii) has antioxidant activity improving endothelial function, (iii) has acidosis properties ( Hayden et al., 2005). The mechanisms of action, by which sodium thiosulfate exerts its inhibitory effect on vascular mineralization, are not yet clear. ![]() ![]() Sodium thiosulfate, also known as sodium hydrosulfite, is used as an antidote to cyanide poisoning ( Baskin et al., 1992), but several studies have demonstrated that its efficacy in some pathological conditions is related to ectopic calcification. Francesco Demetrio Lofaro, in International Review of Cell and Molecular Biology, 2020 5.3 Sodium thiosulfate (STS)
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